Therefore, I declare to you today that I am innocent of the blood of any of you.
It is possible for us to be guilty of another person’s loss of salvation. As Christians, we have the same obligation Paul had to counsel others when we see them doing something that is against Christian teachings. This is not the same as judging, which we are told not to do.
Acts 20:26 Paul is referring to their spiritual death, not physical blood. The wording is reflected in Acts 18:6, when Paul says this about his rejection by the Jewish community in Corinth: “And when they opposed and reviled him, he shook out his garments and said to them, Your blood be upon your heads! I am innocent. From now on I will go to the Gentiles.”
Paul is stating that he taught them God’s truth and warned them when they were wrong; therefore, if they did not listen he was not responsible.
Is it also possible to innocent of another’s loss of salvation? The answer is found in the very next verse: “For I did not shrink from declaring to you the whole counsel of God.” If not teaching is a sin, not wanting to be taught is also a sin. If you tell them God’s truth and they refuse to listen, you are not guilty.